FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ

Nimustine (ACNU) and temozolomide (TMZ) are DNA alkylating agents which are commonly used in chemotherapy for glioblastomas. ACNU is a DNA cross-linking agent and TMZ is a methylating agent. The therapeutic efficacy of these agents is limited by the development of resistance. In this work, the role...

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Bibliographic Details
Main Authors:	Kondo, Natsuko, Takahashi, Akihisa, Mori, Eiichiro, Noda, Taichi, Zdzienicka, Małgorzata Z., Thompson, Larry H., Helleday, Thomas, Suzuki, Minoru, Kinashi, Yuko, Masunaga, Shinichiro, Ono, Koji, Hasegawa, Masatoshi, Ohnishi, Takeo
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2011
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3090409/ https://ncbi.nlm.nih.gov/pubmed/21573016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019659
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FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ

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