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Effects of valproic acid on the susceptibility of human glioma stem cells for TMZ and ACNU

To investigate the effect of valproic acid (VPA) on the susceptibility of glioma stem cells to temozolomide (TMZ) and nimustine (ACNU), the O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and its expression of MGMT were examined. A total of 3 glioma cell populations were isolated...

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Publicat a:Oncol Lett
Autors principals: Li, Zhiying, Xia, Yun, Bu, Xingyao, Yang, Dongyi, Yuan, Yiqiang, Guo, Xiaohe, Zhang, Gangzhong, Wang, Zhanwei, Jiao, Jichao
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958707/
https://ncbi.nlm.nih.gov/pubmed/29805689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8551
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