Effects of valproic acid on the susceptibility of human glioma stem cells for TMZ and ACNU

To investigate the effect of valproic acid (VPA) on the susceptibility of glioma stem cells to temozolomide (TMZ) and nimustine (ACNU), the O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and its expression of MGMT were examined. A total of 3 glioma cell populations were isolated...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Li, Zhiying, Xia, Yun, Bu, Xingyao, Yang, Dongyi, Yuan, Yiqiang, Guo, Xiaohe, Zhang, Gangzhong, Wang, Zhanwei, Jiao, Jichao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958707/
https://ncbi.nlm.nih.gov/pubmed/29805689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8551
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