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Effects of valproic acid on the susceptibility of human glioma stem cells for TMZ and ACNU

To investigate the effect of valproic acid (VPA) on the susceptibility of glioma stem cells to temozolomide (TMZ) and nimustine (ACNU), the O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and its expression of MGMT were examined. A total of 3 glioma cell populations were isolated...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Li, Zhiying, Xia, Yun, Bu, Xingyao, Yang, Dongyi, Yuan, Yiqiang, Guo, Xiaohe, Zhang, Gangzhong, Wang, Zhanwei, Jiao, Jichao
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958707/
https://ncbi.nlm.nih.gov/pubmed/29805689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8551
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