Defective CFTR-Dependent CREB Activation Results in Impaired Spermatogenesis and Azoospermia

Cystic fibrosis (CF) is the most common life-limiting recessive genetic disease among Caucasians caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) with over 95% male patients infertile. However, whether CFTR mutations could affect spermatogenesis and result in azo...

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Detalhes bibliográficos
Main Authors: Xu, Wen Ming, Chen, Jing, Chen, Hui, Diao, Rui Ying, Fok, Kin Lam, Dong, Jian Da, Sun, Ting Ting, Chen, Wen Ying, Yu, Mei Kuen, Zhang, Xiao Hu, Tsang, Lai Ling, Lau, Ann, Shi, Qi Xian, Shi, Qing Hua, Huang, Ping Bo, Chan, Hsiao Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090391/
https://ncbi.nlm.nih.gov/pubmed/21625623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019120
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