Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis

While inflammation with aberrant activation of NF-κB pathway is a hallmark of cystic fibrosis (CF), the molecular mechanisms underlying the link between CFTR defect and activation of NF-κB-mediated pro-inflammatory response remain elusive. Here, we investigated the link between CFTR defect and NF-κB...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Kaisheng, Zhang, Xiaohu, Zhang, Jie Ting, Tsang, Lai Ling, Jiang, Xiaohua, Chan, Hsiao Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325423/
https://ncbi.nlm.nih.gov/pubmed/27588407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11747
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