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Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis
Cystic fibrosis transmembrane conductance regulator (CFTR), known as a cAMP-activated Cl(−) channel, is widely expressed at the apical membrane of epithelial cells in a wide variety of tissues. Of note, despite the abundant expression of CFTR in mammalian kidney, the role of CFTR in kidney disease d...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507915/ https://ncbi.nlm.nih.gov/pubmed/28701694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05435-5 |
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