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Molecular Chaperones as Targets to Circumvent the CFTR Defect in Cystic Fibrosis
Cystic Fibrosis (CF) is the most common autosomal recessive lethal disorder among Caucasian populations. CF results from mutations and resulting dysfunction of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). CFTR is a cyclic AMP-dependent chloride channel that is localized to the api...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398409/ https://ncbi.nlm.nih.gov/pubmed/22822398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00137 |
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