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Non-proteolytic ubiquitylation counteracts the APC/C-inhibitory function of XErp1
Mature Xenopus oocytes are arrested in meiosis by the activity of XErp1/Emi2, an inhibitor of the ubiquitin-ligase anaphase-promoting complex/cyclosome (APC/C). On fertilization, XErp1 is degraded, resulting in APC/C activation and the consequent degradation of cell-cycle regulators and exit from me...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090011/ https://ncbi.nlm.nih.gov/pubmed/21399619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.32 |
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