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Calcineurin promotes APC/C activation at meiotic exit by acting on both XErp1 and Cdc20

Vertebrate oocytes await fertilization arrested at metaphase of the second meiotic division. Fertilization triggers a transient calcium wave, which induces the activation of the anaphase‐promoting complex/cyclosome (APC/C) and its co‐activator Cdc20 resulting in the destruction of cyclin B and hence...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Heim, Andreas, Tischer, Thomas, Mayer, Thomas U
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280790/
https://ncbi.nlm.nih.gov/pubmed/30373936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846433
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