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Protein phosphatase 1 is essential for Greatwall inactivation at mitotic exit
Entry into mitosis is mediated by the phosphorylation of key cell cycle regulators by cyclin-dependent kinase 1 (Cdk1). In Xenopus embryos, the M-phase-promoting activity of Cdk1 is antagonized by protein phosphatase PP2A-B55. Hence, to ensure robust cell cycle transitions, Cdk1 and PP2A-B55 must be...
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| Publié dans: | EMBO Rep |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley & Sons, Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641502/ https://ncbi.nlm.nih.gov/pubmed/26396231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540876 |
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