Daily Treatment with SMTC1100, a Novel Small Molecule Utrophin Upregulator, Dramatically Reduces the Dystrophic Symptoms in the mdx Mouse

BACKGROUND: Duchenne muscular dystrophy (DMD) is a lethal, progressive muscle wasting disease caused by a loss of sarcolemmal bound dystrophin, which results in the death of the muscle fibers leading to the gradual depletion of skeletal muscle. There is significant evidence demonstrating that increa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tinsley, Jonathon M., Fairclough, Rebecca J., Storer, Richard, Wilkes, Fraser J., Potter, Allyson C., Squire, Sarah E., Powell, Dave S., Cozzoli, Anna, Capogrosso, Roberta F., Lambert, Adam, Wilson, Francis X., Wren, Stephen P., De Luca, Annamaria, Davies, Kay E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089598/
https://ncbi.nlm.nih.gov/pubmed/21573153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019189
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados