The FVB Background Does Not Dramatically Alter the Dystrophic Phenotype of Mdx Mice

The mdx mouse is the most frequently used animal model for Duchenne muscular dystrophy (DMD), a fatal muscle disease caused by the loss of dystrophin. Mdx mice are naturally occurring dystrophin-null mice on the C57BL/10 (BL10) background. We crossed black mdx to the white FVB background and generat...

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Bibliographic Details
Published in:PLoS Curr
Main Authors: Wasala, Nalinda B., Zhang, Keqing, Wasala, Lakmini P., Hakim, Chady H., Duan, Dongsheng
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Animal Models
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339318/
https://ncbi.nlm.nih.gov/pubmed/25737807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.md.28266819ca0ec5fefcac767ea9a3461c
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