Effect of genetic background on the dystrophic phenotype in mdx mice

Genetic background significantly affects phenotype in multiple mouse models of human diseases, including muscular dystrophy. This phenotypic variability is partly attributed to genetic modifiers that regulate the disease process. Studies have demonstrated that introduction of the γ-sarcoglycan-null...

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Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Coley, William D., Bogdanik, Laurent, Vila, Maria Candida, Yu, Qing, Van Der Meulen, Jack H., Rayavarapu, Sree, Novak, James S., Nearing, Marie, Quinn, James L., Saunders, Allison, Dolan, Connor, Andrews, Whitney, Lammert, Catherine, Austin, Andrew, Partridge, Terence A., Cox, Gregory A., Lutz, Cathleen, Nagaraju, Kanneboyina
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690497/
https://ncbi.nlm.nih.gov/pubmed/26566673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv460
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