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Effect of the IL-1 Receptor Antagonist Kineret(®) on Disease Phenotype in mdx Mice

Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by mutations in the dystrophin gene. The pathology of DMD manifests in patients with progressive muscle weakness, loss of ambulation and ultimately death. One of the characteristics of DMD is muscle inflammation, and dystrophin-d...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Benny Klimek, Margaret E., Sali, Arpana, Rayavarapu, Sree, Van der Meulen, Jack H., Nagaraju, Kanneboyina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877010/
https://ncbi.nlm.nih.gov/pubmed/27213537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155944
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