Losartan Decreases Cardiac Muscle Fibrosis and Improves Cardiac Function in Dystrophin-Deficient Mdx Mice

Recent studies showed that chronic administration of losartan, an angiotensin II type I receptor antagonist, improved skeletal muscle function in dystrophin-deficient mdx mice. In this study, C57BL/10ScSn-Dmd(mdx)/J female mice were either untreated or treated with losartan (n = 15) in the drinking...

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Detalhes bibliográficos
Main Authors: Spurney, Christopher F., Sali, Arpana, Guerron, Alfredo D., Iantorno, Micaela, Yu, Qing, Gordish-Dressman, Heather, Rayavarapu, Sree, van der Meulen, Jack, Hoffman, Eric P., Nagaraju, Kanneboyina
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147941/
https://ncbi.nlm.nih.gov/pubmed/21304057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1074248410381757
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