Effect of genetic background on the dystrophic phenotype in mdx mice

Genetic background significantly affects phenotype in multiple mouse models of human diseases, including muscular dystrophy. This phenotypic variability is partly attributed to genetic modifiers that regulate the disease process. Studies have demonstrated that introduction of the γ-sarcoglycan-null...

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Bibliografiset tiedot
Julkaisussa:Hum Mol Genet
Päätekijät: Coley, William D., Bogdanik, Laurent, Vila, Maria Candida, Yu, Qing, Van Der Meulen, Jack H., Rayavarapu, Sree, Novak, James S., Nearing, Marie, Quinn, James L., Saunders, Allison, Dolan, Connor, Andrews, Whitney, Lammert, Catherine, Austin, Andrew, Partridge, Terence A., Cox, Gregory A., Lutz, Cathleen, Nagaraju, Kanneboyina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2016
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690497/
https://ncbi.nlm.nih.gov/pubmed/26566673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv460
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