Tumour suppressor ING1b maintains genomic stability upon replication stress

The lesion bypass pathway, which is regulated by monoubiquitination of proliferating cell nuclear antigen (PCNA), is essential for resolving replication stalling due to DNA lesions. This process is important for preventing genomic instability and cancer development. Previously, it was shown that cel...

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Main Authors: Wong, Ronald P. C., Lin, Hanyang, Khosravi, Shahram, Piche, Brad, Jafarnejad, Seyed Mehdi, Chen, David W. C., Li, Gang
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089469/
https://ncbi.nlm.nih.gov/pubmed/21227930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1337
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