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Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin

The replication of the genome is a spatio-temporally highly organized process. Yet, its flexibility throughout development suggests that this process is not genetically regulated. However, the mechanisms and chromatin modifications controlling replication timing are still unclear. We made use of the...

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Autores principales: Casas-Delucchi, Corella S., van Bemmel, Joke G., Haase, Sebastian, Herce, Henry D., Nowak, Danny, Meilinger, Daniela, Stear, Jeffrey H., Leonhardt, Heinrich, Cardoso, M. Cristina
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245938/
https://ncbi.nlm.nih.gov/pubmed/21908399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr723
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