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Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin

The replication of the genome is a spatio-temporally highly organized process. Yet, its flexibility throughout development suggests that this process is not genetically regulated. However, the mechanisms and chromatin modifications controlling replication timing are still unclear. We made use of the...

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Autori principali: Casas-Delucchi, Corella S., van Bemmel, Joke G., Haase, Sebastian, Herce, Henry D., Nowak, Danny, Meilinger, Daniela, Stear, Jeffrey H., Leonhardt, Heinrich, Cardoso, M. Cristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245938/
https://ncbi.nlm.nih.gov/pubmed/21908399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr723
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