Tumour suppressor ING1b maintains genomic stability upon replication stress

The lesion bypass pathway, which is regulated by monoubiquitination of proliferating cell nuclear antigen (PCNA), is essential for resolving replication stalling due to DNA lesions. This process is important for preventing genomic instability and cancer development. Previously, it was shown that cel...

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Detalhes bibliográficos
Principais autores: Wong, Ronald P. C., Lin, Hanyang, Khosravi, Shahram, Piche, Brad, Jafarnejad, Seyed Mehdi, Chen, David W. C., Li, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089469/
https://ncbi.nlm.nih.gov/pubmed/21227930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1337
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