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Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish
The nonsense-mediated mRNA decay (NMD) pathway is a highly conserved surveillance mechanism that is present in all eukaryotes. It prevents the synthesis of truncated proteins by selectively degrading mRNAs harbouring premature termination codons (PTCs). The core NMD effectors were originally identif...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089463/ https://ncbi.nlm.nih.gov/pubmed/21227923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1319 |
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