DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans

The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons but also regulates the abundance of cellular RNAs. We sought to identify transcripts that are regulated by two novel NMD factors, DHX34 and neuroblastoma amplified sequence (NBAS), which...

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Detalhes bibliográficos
Main Authors: Longman, Dasa, Hug, Nele, Keith, Marianne, Anastasaki, Corina, Patton, E. Elizabeth, Grimes, Graeme, Cáceres, Javier F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783168/
https://ncbi.nlm.nih.gov/pubmed/23828042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt585
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