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DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans

The nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons but also regulates the abundance of cellular RNAs. We sought to identify transcripts that are regulated by two novel NMD factors, DHX34 and neuroblastoma amplified sequence (NBAS), which...

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Hlavní autoři: Longman, Dasa, Hug, Nele, Keith, Marianne, Anastasaki, Corina, Patton, E. Elizabeth, Grimes, Graeme, Cáceres, Javier F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783168/
https://ncbi.nlm.nih.gov/pubmed/23828042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt585
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