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Topoisomerase IIα Is Required for Embryonic Development and Liver Regeneration in Zebrafish
Topoisomerases solve the topological problems encountered by DNA throughout the lifetime of a cell. Topoisomerase IIα, which is highly conserved among eukaryotes, untangles replicated chromosomes during mitosis and is absolutely required for cell viability. A homozygous lethal mutant, can4, was iden...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2698760/ https://ncbi.nlm.nih.gov/pubmed/19380487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01684-08 |
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