Topoisomerase IIα Is Required for Embryonic Development and Liver Regeneration in Zebrafish

Topoisomerases solve the topological problems encountered by DNA throughout the lifetime of a cell. Topoisomerase IIα, which is highly conserved among eukaryotes, untangles replicated chromosomes during mitosis and is absolutely required for cell viability. A homozygous lethal mutant, can4, was iden...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dovey, Michael, Patton, E. Elizabeth, Bowman, Teresa, North, Trista, Goessling, Wolfram, Zhou, Yi, Zon, Leonard I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698760/
https://ncbi.nlm.nih.gov/pubmed/19380487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01684-08
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