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Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish
The nonsense-mediated mRNA decay (NMD) pathway is a highly conserved surveillance mechanism that is present in all eukaryotes. It prevents the synthesis of truncated proteins by selectively degrading mRNAs harbouring premature termination codons (PTCs). The core NMD effectors were originally identif...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3089463/ https://ncbi.nlm.nih.gov/pubmed/21227923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1319 |
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