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An Improved Model of the Aspergillus fumigatus CYP51A Protein

Azole resistance is an increasing clinical problem for Aspergillus fumigatus, with the majority of published resistance arising from mutations in the azole target gene CYP51A. Previous structural studies of this protein have suffered from a nonorthologous, low-homology template for homology modeling...

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Detalhes bibliográficos
Main Authors: Fraczek, M. G., Bromley, M., Bowyer, P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088270/
https://ncbi.nlm.nih.gov/pubmed/21300838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01651-10
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