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An Improved Model of the Aspergillus fumigatus CYP51A Protein

Azole resistance is an increasing clinical problem for Aspergillus fumigatus, with the majority of published resistance arising from mutations in the azole target gene CYP51A. Previous structural studies of this protein have suffered from a nonorthologous, low-homology template for homology modeling...

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Bibliografski detalji
Glavni autori: Fraczek, M. G., Bromley, M., Bowyer, P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088270/
https://ncbi.nlm.nih.gov/pubmed/21300838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01651-10
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