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Insight into the Significance of Aspergillus fumigatus cyp51A Polymorphisms

Triazole antifungal compounds are the first treatment choice for invasive aspergillosis. However, in the last decade the rate of azole resistance among Aspergillus fumigatus strains has increased notoriously. The main resistance mechanisms are well defined and mostly related to point mutations of th...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Garcia-Rubio, Rocio, Alcazar-Fuoli, Laura, Monteiro, Maria Candida, Monzon, Sara, Cuesta, Isabel, Pelaez, Teresa, Mellado, Emilia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971592/
https://ncbi.nlm.nih.gov/pubmed/29632011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00241-18
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