A mammalianized synthetic nitroreductase gene for high-level expression

BACKGROUND: The nitroreductase/5-(azaridin-1-yl)-2,4-dinitrobenzamide (NTR/CB1954) enzyme/prodrug system is considered as a promising candidate for anti-cancer strategies by gene-directed enzyme prodrug therapy (GDEPT) and has recently entered clinical trials. It requires the genetic modification of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Grohmann, Maik, Paulmann, Nils, Fleischhauer, Sebastian, Vowinckel, Jakob, Priller, Josef, Walther, Diego J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087338/
https://ncbi.nlm.nih.gov/pubmed/19712451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-301
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados