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Histaminylation of glutamine residues is a novel posttranslational modification implicated in G-protein signaling

Posttranslational modifications (PTM) have been shown to be essential for protein function and signaling. Here we report the identification of a novel modification, protein transfer of histamine, and provide evidence for its function in G protein signaling. Histamine, known as neurotransmitter and m...

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Detalhes bibliográficos
Main Authors: Vowinckel, Jakob, Stahlberg, Silke, Paulmann, Nils, Bluemlein, Katharina, Grohmann, Maik, Ralser, Markus, Walther, Diego J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science B.V 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743044/
https://ncbi.nlm.nih.gov/pubmed/23022564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.09.027
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