Intracellular Serotonin Modulates Insulin Secretion from Pancreatic β-Cells by Protein Serotonylation

While serotonin (5-HT) co-localization with insulin in granules of pancreatic β-cells was demonstrated more than three decades ago, its physiological role in the etiology of diabetes is still unclear. We combined biochemical and electrophysiological analyses of mice selectively deficient in peripher...

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Detalhes bibliográficos
Main Authors: Paulmann, Nils, Grohmann, Maik, Voigt, Jörg-Peter, Bert, Bettina, Vowinckel, Jakob, Bader, Michael, Skelin, Maša, Jevšek, Marko, Fink, Heidrun, Rupnik, Marjan, Walther, Diego J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760755/
https://ncbi.nlm.nih.gov/pubmed/19859528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000229
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