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The triggering pathway to insulin secretion: Functional similarities and differences between the human and the mouse β cells and their translational relevance

In β cells, stimulation by metabolic, hormonal, neuronal, and pharmacological factors is coupled to secretion of insulin through different intracellular signaling pathways. Our knowledge about the molecular machinery supporting these pathways and the patterns of signals it generates comes mostly fro...

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Detalhes bibliográficos
Publicado no:Islets
Main Authors: Skelin Klemen, Maša, Dolenšek, Jurij, Slak Rupnik, Marjan, Stožer, Andraž
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710702/
https://ncbi.nlm.nih.gov/pubmed/28662366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2017.1342022
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