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The triggering pathway to insulin secretion: Functional similarities and differences between the human and the mouse β cells and their translational relevance

In β cells, stimulation by metabolic, hormonal, neuronal, and pharmacological factors is coupled to secretion of insulin through different intracellular signaling pathways. Our knowledge about the molecular machinery supporting these pathways and the patterns of signals it generates comes mostly fro...

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Pubblicato in:Islets
Autori principali: Skelin Klemen, Maša, Dolenšek, Jurij, Slak Rupnik, Marjan, Stožer, Andraž
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710702/
https://ncbi.nlm.nih.gov/pubmed/28662366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2017.1342022
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