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Synthetic control systems for high performance gene expression in mammalian cells

Tunable induction of gene expression is an essential tool in biology and biotechnology. In spite of that, current induction systems often exhibit unpredictable behavior and performance shortcomings, including high sensitivity to transactivator dosage and plasmid take-up variation, and excessive cons...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Lillacci, Gabriele, Benenson, Yaakov, Khammash, Mustafa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182142/
https://ncbi.nlm.nih.gov/pubmed/30203050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky795
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