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Synthetic control systems for high performance gene expression in mammalian cells

Tunable induction of gene expression is an essential tool in biology and biotechnology. In spite of that, current induction systems often exhibit unpredictable behavior and performance shortcomings, including high sensitivity to transactivator dosage and plasmid take-up variation, and excessive cons...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Lillacci, Gabriele, Benenson, Yaakov, Khammash, Mustafa
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182142/
https://ncbi.nlm.nih.gov/pubmed/30203050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky795
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