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Synthetic control systems for high performance gene expression in mammalian cells

Tunable induction of gene expression is an essential tool in biology and biotechnology. In spite of that, current induction systems often exhibit unpredictable behavior and performance shortcomings, including high sensitivity to transactivator dosage and plasmid take-up variation, and excessive cons...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Lillacci, Gabriele, Benenson, Yaakov, Khammash, Mustafa
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182142/
https://ncbi.nlm.nih.gov/pubmed/30203050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky795
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