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Structure of an agonist-bound human A(2A) adenosine receptor
Activation of G protein-coupled receptors upon agonist binding is a critical step in the signaling cascade for this family of cell surface proteins. Here we report the crystal structure of the A(2A) adenosine receptor (A(2A)AR) bound to an agonist UK-432097 at 2.7 angstrom resolution. Relative to in...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086811/ https://ncbi.nlm.nih.gov/pubmed/21393508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1202793 |
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