The Role of Matrix Metalloproteinase-9 in Cigarette Smoke–induced Emphysema

Rationale: Matrix metalloprotease (MMP)-9 is an elastolytic endopeptidase produced by activated macrophages that may be involved in the development of human pulmonary emphysema and could be inhibited with existing compounds. Mouse models have demonstrated that excess MMP-9 production can result in p...

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Autori principali: Atkinson, Jeffrey J., Lutey, Barbara A., Suzuki, Yoko, Toennies, Holly M., Kelley, Diane G., Kobayashi, Dale K., Ijem, Whitney G., Deslee, Gaetan, Moore, Carla H., Jacobs, M. Eileen, Conradi, Susan H., Gierada, David S., Pierce, Richard A., Betsuyaku, Tomoko, Senior, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2011
Soggetti:
B. Chronic Obstructive Pulmonary Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086754/
https://ncbi.nlm.nih.gov/pubmed/21057003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201005-0718OC
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