The Role of Matrix Metalloproteinase-9 in Cigarette Smoke–induced Emphysema

Rationale: Matrix metalloprotease (MMP)-9 is an elastolytic endopeptidase produced by activated macrophages that may be involved in the development of human pulmonary emphysema and could be inhibited with existing compounds. Mouse models have demonstrated that excess MMP-9 production can result in p...

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Bibliografiska uppgifter
Huvudupphovsmän: Atkinson, Jeffrey J., Lutey, Barbara A., Suzuki, Yoko, Toennies, Holly M., Kelley, Diane G., Kobayashi, Dale K., Ijem, Whitney G., Deslee, Gaetan, Moore, Carla H., Jacobs, M. Eileen, Conradi, Susan H., Gierada, David S., Pierce, Richard A., Betsuyaku, Tomoko, Senior, Robert M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2011
Ämnen:
B. Chronic Obstructive Pulmonary Disease
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086754/
https://ncbi.nlm.nih.gov/pubmed/21057003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201005-0718OC
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