Cigarette Smoke Induces Nucleic-Acid Oxidation in Lung Fibroblasts

Oxidative stress is widely proposed as a pathogenic mechanism for chronic obstructive pulmonary disease (COPD), but the molecular pathway connecting oxidative damage to tissue destruction remains to be fully defined. We suggest that reactive oxygen species (ROS) oxidatively damage nucleic acids, and...

Full description

Saved in:

Bibliographic Details
Main Authors:	Deslee, Gaetan, Adair-Kirk, Tracy L., Betsuyaku, Tomoko, Woods, Jason C., Moore, Carla H., Gierada, David S., Conradi, Susan H., Atkinson, Jeffrey J., Toennies, Holly M., Battaile, John T., Kobayashi, Dale K., Patterson, G. Alexander, Holtzman, Michael J., Pierce, Richard A.
Format:	Artigo
Language:	Inglês
Published:	American Thoracic Society 2010
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2970854/ https://ncbi.nlm.nih.gov/pubmed/20008282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0221OC
Tags:	Add Tag No Tags, Be the first to tag this record!

Cigarette Smoke Induces Nucleic-Acid Oxidation in Lung Fibroblasts

Similar Items