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Cigarette Smoke Induces Nucleic-Acid Oxidation in Lung Fibroblasts
Oxidative stress is widely proposed as a pathogenic mechanism for chronic obstructive pulmonary disease (COPD), but the molecular pathway connecting oxidative damage to tissue destruction remains to be fully defined. We suggest that reactive oxygen species (ROS) oxidatively damage nucleic acids, and...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Thoracic Society
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970854/ https://ncbi.nlm.nih.gov/pubmed/20008282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0221OC |
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