The Role of Matrix Metalloproteinase-9 in Cigarette Smoke–induced Emphysema

Rationale: Matrix metalloprotease (MMP)-9 is an elastolytic endopeptidase produced by activated macrophages that may be involved in the development of human pulmonary emphysema and could be inhibited with existing compounds. Mouse models have demonstrated that excess MMP-9 production can result in p...

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Detalhes bibliográficos
Principais autores: Atkinson, Jeffrey J., Lutey, Barbara A., Suzuki, Yoko, Toennies, Holly M., Kelley, Diane G., Kobayashi, Dale K., Ijem, Whitney G., Deslee, Gaetan, Moore, Carla H., Jacobs, M. Eileen, Conradi, Susan H., Gierada, David S., Pierce, Richard A., Betsuyaku, Tomoko, Senior, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
B. Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086754/
https://ncbi.nlm.nih.gov/pubmed/21057003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201005-0718OC
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