Oxidative Damage to Nucleic Acids in Severe Emphysema*

BACKGROUND: Oxidative stress is a key element in the pathogenesis of emphysema, but oxidation of nucleic acids has been largely overlooked. The aim of this study was to investigate oxidative damage to nucleic acids in severe emphysematous lungs. METHODS: Thirteen human severe emphysematous lungs, in...

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Hauptverfasser: Deslee, Gaetan, Woods, Jason C., Moore, Carla, Conradi, Susan H., Gierada, David S., Atkinson, Jeffrey J., Battaile, John T., Liu, Lucy, Patterson, G. Alexander, Adair-Kirk, Tracy L., Holtzman, Michael J., Pierce, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864580/
https://ncbi.nlm.nih.gov/pubmed/19118262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.08-2257
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