E-Cadherin Antagonizes Transforming Growth Factor β1 Gene Induction in Hepatic Stellate Cells by Inhibiting RhoA–Dependent Smad3 Phosphorylation

Cadherins mediate cell-cell adhesion and catenin (ctn)-related signaling pathways. Liver fibrosis is accompanied by the loss of E-cadherin (ECAD), which promotes the process of epithelial-mesenchymal transition. Currently, no information is available about the inhibitory role of ECAD in hepatic stel...

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Detalhes bibliográficos
Main Authors: Cho, Il Je, Kim, Young Woo, Han, Chang Yeob, Kim, Eun Hyun, Anderson, Richard A., Lee, Young Sok, Lee, Chang Ho, Hwang, Se Jin, Kim, Sang Geon
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086490/
https://ncbi.nlm.nih.gov/pubmed/20890948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23931
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