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RhoA phosphorylation mediated by Rho/RhoA-associated kinase pathway improves the anti-freezing potentiality of murine hatched and diapaused blastocysts

Embryonic cryopreservation has a relatively low survival rate because of cytoskeletal damage. However, molecular anti-freezing mechanisms have been largely unexplored. This study investigated the significance of RhoA, involved in embryonic development, and the Rho/RhoA-associated kinase (ROCK) signa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gu, Meichao, Ni, Hemin, Sheng, Xihui, Pauciullo, Alfredo, Liu, Yunhai, Guo, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532275/
https://ncbi.nlm.nih.gov/pubmed/28751650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07066-2
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