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PKCε Phosphorylates and Mediates the Cell Membrane Localization of RhoA
Protein kinase Cε (PKCε) signals through RhoA to modulate cell invasion and motility. In this study, the multifaceted interaction between PKCε and RhoA was defined. Phosphopeptide mapping revealed that PKCε phosphorylates RhoA at T127 and S188. Recombinant PKCε bound to recombinant RhoA in the absen...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Hindawi Publishing Corporation
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804392/ https://ncbi.nlm.nih.gov/pubmed/24191200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/329063 |
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