PKCε Phosphorylates and Mediates the Cell Membrane Localization of RhoA

Protein kinase Cε (PKCε) signals through RhoA to modulate cell invasion and motility. In this study, the multifaceted interaction between PKCε and RhoA was defined. Phosphopeptide mapping revealed that PKCε phosphorylates RhoA at T127 and S188. Recombinant PKCε bound to recombinant RhoA in the absen...

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Detalhes bibliográficos
Main Authors: Su, Tizhi, Straight, Samuel, Bao, Liwei, Xie, Xiujie, Lehner, Caryn L., Cavey, Greg S., Teknos, Theodoros N., Pan, Quintin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804392/
https://ncbi.nlm.nih.gov/pubmed/24191200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/329063
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