Cisplatin pharmacogenetics, DNA repair polymorphisms, and esophageal cancer outcomes

OBJECTIVES: Genetic variations or polymorphisms within genes of the nucleotide excision repair (NER) pathway alter DNA repair capacity. Reduced DNA repair (NER) capacity may result in tumors that are more susceptible to cisplatin chemotherapy, which functions by causing DNA damage. We investigated t...

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Библиографические подробности
Главные авторы: Bradbury, Penelope A., Kulke, Matthew H., Heist, Rebecca S., Zhou, Wei, Ma, Clement, Xu, Wei, Marshall, Ariela L., Zhai, Rihong, Hooshmand, Susanne M., Asomaning, Kofi, Su, Li, Shepherd, Frances A., Lynch, Thomas J., Wain, John C., Christiani, David C., Liu, Geoffrey
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085844/
https://ncbi.nlm.nih.gov/pubmed/19620936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32832f3010
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