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Polymorphisms of the NER pathway genes, ERCC1 and XPD are associated with esophageal adenocarcinoma risk

PURPOSE: Functional variation in DNA repair capacity through single nucleotide polymorphisms (SNPs) of key repair genes is associated with a higher risk of developing various types of cancer. Studies have focused on the nucleotide excision repair (NER) and base excision repair (BER) pathways. We inv...

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Detalhes bibliográficos
Main Authors: Tse, Darren, Zhai, Rihong, Zhou, Wei, Heist, Rebecca S., Asomaning, Kofi, Su, Li, Lynch, Thomas J., Wain, John C., Christiani, David C., Liu, Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106102/
https://ncbi.nlm.nih.gov/pubmed/18478337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-008-9171-4
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