p53 Arg72Pro and MDM2 T309G Polymorphisms, Histology, and Esophageal Cancer Prognosis

PURPOSE: This study aimed to evaluate the prognostic significance of two functional single nucleotide polymorphisms (SNP) in the p53 pathway (p53 Arg72Pro and MDM2 T309G) in patients with esophageal cancer, and to determine the importance of histologic subtype in the SNP-outcome relationships. EXPER...

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Bibliografiske detaljer
Main Authors: Cescon, David W., Bradbury, Penelope A., Asomaning, Kofi, Hopkins, Jessica, Zhai, Rihong, Zhou, Wei, Wang, Zhaoxi, Kulke, Matthew, Su, Li, Ma, Clement, Xu, Wei, Marshall, Ariela L., Heist, Rebecca Suk, Wain, John C., Lynch, Thomas J., Christiani, David C., Liu, Geoffrey
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081782/
https://ncbi.nlm.nih.gov/pubmed/19383811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3120
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