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p53 Arg72Pro and MDM2 T309G Polymorphisms, Histology, and Esophageal Cancer Prognosis

PURPOSE: This study aimed to evaluate the prognostic significance of two functional single nucleotide polymorphisms (SNP) in the p53 pathway (p53 Arg72Pro and MDM2 T309G) in patients with esophageal cancer, and to determine the importance of histologic subtype in the SNP-outcome relationships. EXPER...

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Hlavní autoři: Cescon, David W., Bradbury, Penelope A., Asomaning, Kofi, Hopkins, Jessica, Zhai, Rihong, Zhou, Wei, Wang, Zhaoxi, Kulke, Matthew, Su, Li, Ma, Clement, Xu, Wei, Marshall, Ariela L., Heist, Rebecca Suk, Wain, John C., Lynch, Thomas J., Christiani, David C., Liu, Geoffrey
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081782/
https://ncbi.nlm.nih.gov/pubmed/19383811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3120
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