Hydroxydibenzoylmethane induces apoptosis through repressing ornithine decarboxylase in human promyelocytic leukemia HL-60 cells

Ornithine decarboxylase (ODC) is the rate-limiting enzyme in polyamine biosynthesis and a target for chemoprevention. Hydroxydibenzoylmethane (HDB), a derivative of dibenzoylmethane of licorice, is a promising chemopreventive agent. In this paper, we investigated whether HDB would inhibit the ODC pa...

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Bibliografiske detaljer
Main Authors: Wang, Ming-Fu, Liao, Ya-Fan, Hung, Ying-Cheng, Lin, Chih-Li, Hour, Tzyh-Chyuan, Lue, Ko-Huang, Hung, Hui-Chih, Liu, Guang-Yaw
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2011
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085737/
https://ncbi.nlm.nih.gov/pubmed/21372632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.4.023
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