Diversity-oriented synthesis of macrocyclic peptidomimetics

Structurally diverse libraries of novel small molecules represent important sources of biologically active agents. In this paper we report the development of a diversity-oriented synthesis strategy for the generation of diverse small molecules based around a common macrocyclic peptidomimetic framewo...

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Auteurs principaux: Isidro-Llobet, Albert, Murillo, Tiffanie, Bello, Paula, Cilibrizzi, Agostino, Hodgkinson, James T., Galloway, Warren R. J. D., Bender, Andreas, Welch, Martin, Spring, David R.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Organic Synthesis Toward Small-Molecule Probes and Drugs Special Feature
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084124/
https://ncbi.nlm.nih.gov/pubmed/21383137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015267108
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