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Route to three-dimensional fragments using diversity-oriented synthesis
Fragment-based drug discovery (FBDD) has proven to be an effective means of producing high-quality chemical ligands as starting points for drug-discovery pursuits. The increasing number of clinical candidate drugs developed using FBDD approaches is a testament of the efficacy of this approach. The s...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084099/ https://ncbi.nlm.nih.gov/pubmed/21482811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015271108 |
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