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Creation and manipulation of common functional groups en route to a skeletally diverse chemical library
We have developed an efficient strategy to a skeletally diverse chemical library, which entailed a sequence of enyne cycloisomerization, [4 + 2] cycloaddition, alkene dihydroxylation, and diol carbamylation. Using this approach, only 16 readily available building blocks were needed to produce a repr...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084086/ https://ncbi.nlm.nih.gov/pubmed/21383124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015253108 |
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